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Comparison Of Health-Related Quality Of Life (QOL) Parameters In Patients Undergoing Three Different Surgical Approaches To Radical Prostatectomy At A Single Institution With At Least 12 Months Follow-Up
Scott G Hubosky, Sr.*, Michael D Fabrizio, J. W. Davis*, R. W. Given, Donald F. Lynch, Jr., B. B. Gambill*, Paul F. Schellhammer Devine-Tidewater Urology, Norfolk, VA
Objectives: Since 2004, our institution had adopted Robotic-assisted prostatectomy (RAP) as standard of care for surgical treatment of localized prostate cancer. Subsequently, our volume of prostatectomies has doubled while open radical prostatectomy (ORP) is now rarely performed. Health-related Quality of Life (QOL) must be evaluated in new prostate cancer treatments such as RAP. Methods: A prospective, longitudinal survey of newly diagnosed men with prostate cancer undergoing surgical treatment was performed between 2001-2005. A validated QOL questionnaire, the UCLA Prostate Cancer Index (PCI) was administered prior to surgery and again at 1,3,6,9,12 18 and 24 months after treatment. We compared percent of baseline score (%BS) for various disease-specific domains over different post-surgical intervals. Results: A total of 147, 130, and 133 patients returned a baseline and at least one post-treatment survey for ORP, LRP and RAP respectively. Patients did not differ significantly with regard to age, baseline domain scores, PSA, Gleason score or clinical stage. All domains dropped from baseline values at 1 month but trended back towards baseline with time. At 12 months, %BS in urinary function (UF) was 75% for ORP and LRP but was 68% with RAP(p=0.64). %BS in sexual function at 12 months was 42% for ORP, 35% for LRP and 41% for RAP (p=0.42). Conclusions: QOL parameters appear equivalent among these surgical approaches. With improved magnification and less blood loss, RAP may show improved results with longer follow up and experience beyond the learning curve.
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