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Age-Stratified Functional Outcomes After Laparoscopic Radical Prostatectomy
Craig G Rogers1, Li-Ming Su1, Richard E. Link2, Wendy Sullivan1, Andrew Wagner1, Christian P. Pavlovich1
1Johns Hopkins University School of Medicine, Baltimore, MD;2Baylor College of Medicine, Houston, TX
Introduction: We assessed health-related quality of life after laparoscopic radical prostatectomy (LRP) in men under 50 years of age compared with that of older men.
Materials and Methods: We prospectively assessed urinary continence and potency for 369 men of different age groups (<50 years, 50-59 years, and ≥60 years) by analyzing answers to the Expanded Prostate Cancer Index Composite (EPIC) questionnaire collected preoperatively and at 3, 6, and 12 months after LRP.
Results: Younger men were more likely to achieve urinary continence at one year after LRP using a continence criterion of ≤1 pad per day (100% of men under 50 years; 91% of men 50-59 years; 81% of men ≥60 years, p<0.01). Younger men were more likely to be engaging in intercourse one year after bilateral nerve-sparing LRP (70% of men under 50 years; 67% of men 50-59 years; 46% of men ≥60 years, p<0.01). The mean percent return to baseline urinary continence subscale score at one year was 80% for men <50 years, 79% for men 50-59 years, and 74% for men ≥60 years of age. The mean percent return to baseline sexual function subscale score at one year was 68% for men <50 years, 65% for men 50-59 years, and 58% for men ≥60 years of age.
Conclusions: Men treated for prostate cancer by nerve-sparing LRP who are under 50 years of age report better potency and continence outcomes compared to older men over the first postoperative year after LRP.
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